Nerve fibers regrowing

The Sofroniew Laboratory

Previously injured nerve fibers (in red) are shown re-growing through a dense astrocyte scar (in green) and around the edges of a biomaterial depot (in blue). The growth occurred after the release of growth factors by the biomaterial depot. New research shows that when astrocyte scar formation is genetically prevented, this sort of stimulated nerve fiber regeneration does not occur, indicating that not only is the astrocyte scar not a barrier to regeneration (as previously thought), but that it actually helps to support regeneration.

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