Nobel laureate Randy Schekman to give David S. Sigman Memorial Lecture Feb. 21 at UCLA
Randy Schekman, who was awarded the 2013 Nobel Prize in physiology or medicine, will present UCLA's 2014 David S. Sigman Memorial Lecture on Friday, Feb. 21 at 3 p.m. in the auditorium of the California NanoSystems Institute.
Schekman's talk, "Isolation of an Early Intermediate in Development of the Autophagosome," will focus on the autophagosome, an intracellular compartment enclosed by a membrane, which digests damaged or dysfunctional components of the cell.
The lecture, which is hosted by UCLA's Molecular Biology Institute, is free and open to the public, and reservations are not required.
Schekman won the Nobel Prize for his role in revealing the machinery that regulates the transport and secretion of proteins in our cells. His basic science research holds promise for understanding neurological and immunological disorders.
A professor of molecular and cell biology, Schekman has served on UC Berkeley's faculty for 37 years and has been a Howard Hughes Medical Institute investigator since 1991. He is a member of the National Academy of Sciences and editor-in-chief of eLife, an open-access online science journal. He earned his bachelor's degree in the life sciences from the UCLA College of Letters and Science in 1971.
The Sigman Memorial Lecture was established in 2002 to honor the memory of David Sigman, a UCLA professor in the departments of biological chemistry and of chemistry and biochemistry, and a charter member and associate director of the UCLA Molecular Biology Institute. Sigman, who died in 2001, was a leader in the field of chemical biology at UCLA and discovered chemical nucleases in a career that illuminated the molecular mechanisms of catalysis.
An endowed fund for the annual award was made possible by contributions from more than 200 of Sigman's colleagues, friends and family, as well as corporate donations from the Amgen Foundation, Eli Lilly and Co., the Bristol-Myers Squibb Foundation and Raytheon Systems Co.