The research, conducted at the UCLA Alzheimer’s and Dementia Care Program, also shows that the program was cost-neutral after accounting for its costs.
The study is the most comprehensive published effort to date to identify the source of neurodegeneration across species.
The research by Dr. Lin Jiang and his team included findings from computer software that assisted them in the drug selection process.
The study not only revealed the promise of goal attainment in dementia care, but also the importance of goal setting for caregivers, who are affected both emotionally and physically by their loved one’s illness.
Study predicts most people with earliest Alzheimer’s signs won’t develop dementia associated with the disease
The research “may reassure some people that despite testing positive on screening tests, their chances of developing Alzheimer’s disease dementia is low,” said UCLA’s Ron Brookmeyer.
UCLA research provides critical knowledge for medicinal chemists to begin designing new drugs based on cambinol that are more potent than the molecule itself.
“This new tool makes possible experiments that we have been wanting to perform for many years,” said UCLA professor Baljit Khakh.
The scientists have shown in their research on mice that increasing levels of a protein could make immune cells more effective at fighting disease.
If replicated in larger studies, the findings could lead to new types of programs to improve mental agility in older adults by combining mental training with physical fitness.
A UCLA study has found that moderate daily walks improve attention and mental skills for adults ages 60 and older.
47 million Americans already demonstrate some evidence of susceptibility to the disease.
The scientists believe the technique, which focuses on cells’ mitochondria, could eventually lead to a way to delay the onset of Parkinson’s disease, Alzheimer’s disease and cancer.
UCLA School of Nursing researchers found that people with a certain genetic variation who took donepezil for the condition had a faster cognitive decline than those who took a placebo.
The discovery could have important implications for treating white matter strokes, a major cause of dementia that also accelerate Alzheimer’s disease.
Neuroscientists at UCLA have developed a new technique for studying a particular type of cell in the brain known as an astrocyte that may play a role in diseases such as Lou Gehrig’s disease and Alzheimer's disease.
UCLA researchers note that the next decade shows great promise for things like improving food safety, fighting infections, storing energy and supplying clean energy.
The research is the first to demonstrate how lifestyle factors directly influence abnormal proteins in people with subtle memory loss who have not yet been diagnosed with dementia.
UCLA researchers found that physical activity particularly affected the size of the hippocampus, which is the part of the brain controlling short-term memory.
The study is the first to look at disease progression in the synapses, where brain cells transmit impulses.
Finding may have implications for preventing stroke and diagnosing Alzheimer’s disease earlier.
One of the three variations appears to be fundamentally a different condition than the other two, said Dr. Dale Bredesen, a UCLA professor of neurology.
The money will fund a new collaboration among primary care clinics, community-based organizations and educational institutions throughout Riverside County.
UCLA researchers help create ‘gold standard’ method for measuring a key early sign of Alzheimer’s disease
The finding marks the final step in an international consortium’s successful effort to develop a unified and reliable approach to assessing signs of Alzheimer’s-related neurodegeneration through structural imaging tests.
Development of a blood test to diagnose the disease would have the advantage of being safe, affordable and easy to administer in large groups or in rural areas.
The research could explain why people with Down syndrome face a higher risk of developing Alzheimer’s disease and also have a shorter lifespan.