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Researchers discover method to stabilize X chromosomes in human embryonic stem cells
The team found a way to correct the instability by resetting the stem cells from a later stage of development to an earlier stage. These results could have great impact on the creation of healthy tissues to cure disease.
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Genetic factors control regenerative properties of blood-forming stem cells, UCLA studies show
The findings could one day lead to improved therapies for people undergoing chemotherapy and radiation treatment for cancer.
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Researchers discover how to prevent calcification of heart tissue
UCLA scientists have found that calcification of heart muscle tissue is caused when a type of cell called cardiac fibroblasts go awry.
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UCLA researchers use stem cells to grow 3-D lung-in-a-dish
The laboratory-grown tissue can be used to study diseases including idiopathic pulmonary fibrosis, which has traditionally been difficult to study using conventional methods.
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Less developed human stem cells are found to metabolize more sugar
The least developed human embryonic stem cells, or “naïve” pluripotent stem cells, consume more sugar than “primed” pluripotent stem cells, which are embryonic stem cells from later in development, researchers have discovered.
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Scientists develop new way to measure important chemical modification on RNA
A team of scientists including researchers from UCLA has developed an RNA sequencing technique that could advance scientists’ use of stem cells in regenerative medicine.
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Metabolic molecule speeds up process by which stem cells differentiate
Scientists at the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have discovered that a certain metabolic molecule helps pluripotent stem cells mature faster.
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UCLA Duchenne muscular dystrophy research receives grant from California’s stem cell agency
The two-year, $2.15 million grant from the California Institute for Regenerative Medicine will fund research by April Pyle, Melissa Spencer and Huan Meng.
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Curing 'bubble baby' disease: From the lab to the clinic
Because of the pioneering work of Dr. Donald Kohn, a researcher with UCLA's Broad Stem Cell Research Center, the potential to bring stem cell therapies to patients is now a reality.
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UC regents appoint Dr. Owen Witte University Professor
Witte’s accomplishments include impactful scientific discoveries, advocacy for science education funding and exemplary leadership.
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Stem cell advance could be key step toward treating deadly blood diseases
UCLA researchers pinpointed the function of a cluster of specialized genes that play a key role in creating and preserving hematopoietic stem cells and identified the process by which those genes are activated.
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UCLA scientists pinpoint cancer gene responsible for neuroendocrine prostate cancer
The researchers found that an experimental drug called CD532, which changes the structure of a key protein, reduced the size of tumors in mice by 80 percent.
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UCLA stem cell researcher receives $7.6 million grant
Funding from the California Institute for Regenerative Medicine will support work to genetically engineer immune cells to fight cancer.
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Cellular protein plays important role in aggressive childhood cancer
Discovery is an important step in the effort to better understand and treat aggressive childhood leukemia.
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Stem cell gene therapy could be key to treating Duchenne muscular dystrophy
The study was the first to create corrected human iPS cells that could directly restore functional muscle tissue affected by the disease.
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Standard method for deriving stem cells may be better for use in regenerative medicine
Discovery provides scientists with critical information on the best way to create stem cells for purposes such as cell transplantation or organ regeneration.
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UCLA researchers make progress toward healing scarred hearts
The research is a significant step forward in the use of human embryonic stem cells for heart regeneration.
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UCLA study identifies potential therapeutic targets for metastatic prostate cancer
The discovery could point the way toward new drugs that slow or stop the disease from spreading.
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UCLA researchers discover more than 3,000 genes in a little-studied part of the human genome
Using Broad Stem Cell Research Center’s cell isolation and genetic sequencing technologies and sophisticated bioinformatics, scientists identify elusive LncRNA genes.
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UCLA-led study shows deadly prostate cancer cells have stem cell qualities
Researchers say this research gives important insight into the cellular nature of aggressive prostate cancer, which will aid in the development of better treatments.
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UCLA stem cell scientist and anti-bullying advocate featured on ESPN
The sports network told the story of how Andrew Goldstein’s courageous story of coming out as gay to his college lacrosse teammates many years ago led to a friendship with a boy who contemplated suicide after coming out.
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UCLA stem cell researchers receive $7.4 million to study immunodeficiency disorder
The award from the California Institute for Regenerative Medicine will fund a phase I/II clinical trial that will enroll 10 patients with an immunodeficiency disorder at three different U.S. locations.
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Stem cell gene therapy developed at UCLA holds promise for eliminating HIV infection
The findings strongly suggest that stem cell-based gene therapy with a chimeric antigen receptor may be an effective treatment for chronic HIV infection in humans.
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UCLA study reveals bone-building protein’s impact on bone stem cells
Results could one day have an impact on the development of a treatment for osteoporosis as well as potentially help those with traumatic bone injuries.
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UCLA study finds cells that become sperm or eggs in humans are vulnerable during pregnancy
Research by scientists at the Broad Stem Cell Research Center shows that the cells carrying parents’ genes to a child are unprotected during part of the prenatal stage of development.
- Wednesday, October 17, 2018