Segment of protein that forms amyloid fibers in Alzheimer's
Crystal structure of a segment from the amyloid-beta protein that forms amyloid fibers in Alzheimer's disease.
Normally the two protein sheets are tightly associated in the spine of the fiber but in this case orange-G has wedged its way between the two sheets.
(Credit: David Eisenberg, director of the UCLA-DOE Institute of Genomics & Proteomics, Howard Hughes Medical Institute investigator, and UCLA postdoctoral fellow Meytal Landau)