CTE progression

David Geffen School of Medicine at UCLA

PET scan brain images show four distribution patterns (T1-T4) of the FDDNP signals that reflect different levels of abnormal brain proteins (tau and amyloid). According to researchers, the patterns may signify early (T1) to advanced (T4) stages of CTE as reflected by increased levels of the abnormal proteins. For comparison, the first PET scan (far left) shows a normal brain and the last PET scan (far right) reflects  an  Alzheimer’s patient’s brain.

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