Muscle cells with and without dystrophin

UCLA Broad Stem Cell Research Center

Top row: skeletal muscle without dystrophin. Left to right: skeletal muscle nuclei (blue), skeletal muscle (red), missing dystrophin, overlay of all three images to the left .

Bottom row: skeletal muscle with restored dystrophin after application of the CRISPR/Cas9 platform. Left to right: skeletal muscle nuclei (blue), skeletal muscle (red), dystrophin (green), Overlay of all three images to the left. Dystrophin appears yellow in overlay image.

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