Microscopy image of a human stem cell-derived hippocampal organoid. When the tissue carries an epilepsy-causing variant in the SCN8A gene, inhibitory neurons (seen in red) are disrupted, and hippocampal brainwave activity patterns are altered.
Kevin Lozano, Samarasinghe lab
Microscopy image of a human stem cell-derived hippocampal organoid. When the tissue carries an epilepsy-causing variant in the SCN8A gene, inhibitory neurons (seen in red) are disrupted, and hippocampal brainwave activity patterns are altered.