genetics

The award from the John Templeton Foundation will help researchers address how much power individuals have over their own health.

The study suggests a new possible framework for treating people with familial hypercholesterolemia, an inherited condition characterized by extremely high levels of LDL, the so-called “bad cholesterol.”

UCLA researchers’ study using zebrafish shows how the disease turns a repair mechanism into one that damages nerve cells. The findings could lead to treatments to prevent nerve damage in leprosy and other diseases.

Professor Douglas Black and colleagues found that not all protein aggregates in brain cells are toxic.

UCLA was among the first medical centers to use exome sequencing, which can analyze more than 20,000 genes at once.

An international team led by researchers from UCLA and Massachusetts General Hospital helped lead discovery of the first definitive genetic mutations.

UCLA researchers observed that mice with a form of autism had an inability to adapt to repeated whisker stimulation.

UCLA research findings show changes in same genes that clipped the sea bird’s wings cause human bone disorders.

Deletions or duplications of DNA along 22nd chromosome hint at biological underpinnings of these neuropsychiatric disorders.

The finding represents one of the clearest examples to date of the phenomenon — stretches of DNA that exist for no reason other than promoting their own inheritance — at the molecular level.

CancerLocator, developed by UCLA researchers, was superior in detecting cancer in blood samples containing low levels of target DNA, which reflect early-stage disease.

Adenosine deaminase-deficient severe combined immunodeficiency is a rare and life-threatening condition that can be fatal within the first year of life if left untreated.

The researchers identified genes that they believe control hundreds of other genes linked to Alzheimer’s disease, Parkinson’s disease, depression and several other disorders.

UCLA School of Nursing researchers found that people with a certain genetic variation who took donepezil for the condition had a faster cognitive decline than those who took a placebo.

The device, developed by UCLA’s Aydogan Ozcan and colleagues in Sweden, could be manufactured for less than $500 each — far less expensive than the equipment that labs use for the same tests.

Neuroscientists at UCLA have developed a new technique for studying a particular type of cell in the brain known as an astrocyte that may play a role in diseases such as Lou Gehrig’s disease and Alzheimer's disease.

The findings could one day lead to improved therapies for people undergoing chemotherapy and radiation treatment for cancer.

A UCLA study used 3D chromosome-mapping technology to advance understanding of disorder’s cause. The work provides important new information about how schizophrenia originates and could lead to better treatments.

In a first-of-its-kind study, UCLA-led researchers have discovered a gene variant that could be a factor in determining which women experience the symptom.

UCLA-led study will offer scientists insights into how cells and organs work when people are ill and healthy.

The discovery opens up a new avenue of research into autism’s causes and potential therapies.

The technique involved amplifying a protein signal without using enzymes, which takes the process from two to four hours down to 10 minutes.

Scientists find new autism-linked gene, and discover that autistic siblings don’t always have the same disease-related mutations.

From the capuchin monkeys of Costa Rica to the Los Angeles area's mountain lions, UCLA experts are developing new techniques and advancing knowledge.

A team of scientists including researchers from UCLA has developed an RNA sequencing technique that could advance scientists’ use of stem cells in regenerative medicine.