LL37 molecules, which are found in the immune system, play an important but unexpected role in revving up the body’s self-defense response.
“This is a pervasive, global problem.... It’s in all types of landscapes — urban, rural and even untouched environments,” says Seth Riley, a co-author of the research.
Jacobsen specializes in plant epigenetics — the study of how a gene’s function can change without changes to the DNA sequence.
The study is the most comprehensive published effort to date to identify the source of neurodegeneration across species.
The life scientists have provided the first cell “atlas” of the hippocampus — the part of the brain that helps regulate learning and memory — when it is affected by traumatic brain injury.
The research by Dr. Lin Jiang and his team included findings from computer software that assisted them in the drug selection process.
Researchers from the School of Dentistry and the David Geffen School of Medicine will use a technology created in the lab of Dr. David Wong from the dental school.
The work and day-to-day activities of UCLA anthropologist Susan Perry and her team are captured on HowtoBeAMonkey.org.
UCLA researchers have found that an often overlooked component of a cell, the extracellular matrix, can influence how much sugar the cell consumes and its migratory behavior.
“We expect several of these combinations, or more, will work much better than existing antibiotics,” said Pamela Yeh, one of the study’s two senior authors and a UCLA assistant professor of ecology and evolutionary biology.
The research provides the first direct evidence of the proteins moving through PTEX, the protein complex that transports malaria proteins into the red blood cell.
Research by UCLA and others finds that the crayfish disrupt native predators that eat mosquito larvae.
The findings could lead to new methods to help prevent clots and repair damage that can result from the placement of stents.
The finding by a UCLA team may lead to new ways to convert petroleum waste into useful compounds.
Research has implications for health and disease, teamwork and collective behavior.
A detailed view of its core may lead to the development of targeted drugs.
The study is the first to establish a link between susceptibility to seizures and the gut microbiota — the 100 trillion or so bacteria and other microbes that reside in the human body’s intestines.
The research in marine snails could lead to new treatments to restore memories and alter traumatic ones in people with Alzheimer's disease and those dealing with post-traumatic stress disorder.
Researchers led by UCLA’s Dr. Paul Krebsbach are the first to characterize the mechanism of the gene, and they found it regulates the molecular process that dictates cell growth and human development.
The team used molecular engineering to develop vaccines that use a common delivery method, or “single vector,” to carry protective antigens to the immune system.
The technique that uses cryo-electron microscopy should help scientists better understand disease-causing proteins.
The research explains concepts that were described nearly 90 years ago but had remained poorly understood until now.
The statistical analysis software the researchers have designed is more precise and reliable than previous methods.
The findings of this study could lead to the creation of new treatments for speech problems in people, including children with autism.
Their technique would enable an average biochemistry laboratory to make its own sequences for only about $2 per gene, far less than the $50 to $100 per gene commercial vendors charge.