UCLA researchers studied FDDNP, a molecular tracer that binds with proteins called tau and amyloid, and which indicates the location and extent of abnormal proteins in the brain.
Two discoveries — one in the brains of people with heroin addiction and the other in the brains of sleepy mice — shed light on chemical messengers that regulate sleep and addiction, UCLA researchers say.
The research “may reassure some people that despite testing positive on screening tests, their chances of developing Alzheimer’s disease dementia is low,” said UCLA’s Ron Brookmeyer.
The award from the Patient-Centered Outcomes Research Institute will be used to compare care delivered through a health system with care that occurs in a community-based setting.
UCLA research provides critical knowledge for medicinal chemists to begin designing new drugs based on cambinol that are more potent than the molecule itself.
If the findings are replicated, measuring levels of interleukin 6 could help doctors decide which patients with depression would be best suited for treatment with ECT.
If replicated in larger studies, the findings could lead to new types of programs to improve mental agility in older adults by combining mental training with physical fitness.
“If the results ... are replicated in future studies, the methods we used could potentially give clinicians a new predictive tool,” said UCLA doctoral student Nicco Reggente.
The substance’s beneficial properties might be due to its ability to reduce inflammation, which has been linked to both Alzheimer’s disease and major depression, according to Dr. Gary Small.
The study shows that treatments tailored for different disabilities caused by MS could be more effective than treatments intended to target multiple different disabilities.
Protein-imaging method developed by new UCLA researcher overcomes challenges of current techniques, offering untold potential in the exploration of disease and treatment.
The study sheds light on the relationship of theta oscillations to human learning and exploration — and it could help inform future research on therapies for patients with memory disorders like Alzheimer’s disease.
A UCLA digital artist and neuroscientist collaborated to create a performance art installation in which participants explore unspoken, visual communication.
A new study is the first to reveal how sleep deprivation disrupts our brain cells’ ability to communicate with each other, which scientists believe leads to temporary mental lapses.