The study could eventually lead to more treatment options for leukemia, sickle cell disease and other conditions.
The oral medication, ERAS-801, targets a rogue gene found in about 60% of people with the aggressive form of brain cancer.
The findings could improve doctors’ ability to offer truly personalized cancer therapy.
A UCLA study suggests that new small-molecule drugs that inhibit a protein called ATR could be used in combination with interferon “amplification.”
The veteran firefighter, who expects to earn his Ph.D. in chemistry in winter quarter, is using his knowledge to improve the health and safety of his colleagues.
Using stem cell engineering and organoid technology, UCLA researchers were able to produce large quantities of powerful cancer-fighting iNKT cells.
A team led by UCLA scientists found that removing IGF2BP3 selectively targets cancer cells while leaving healthy cells alone.
UCLA researchers discover that MAOIs could activate immune system to shrink various types of tumors.
The research, conducted on mice, targets a newly discovered molecular “checkpoint” that enables cancer stem cells to evade the immune system.
Overweight children participating in the intervention were 70% less likely to have detectable cancer cells after one month of treatment.
Only 1 in 10 people diagnosed with this aggressive disease live beyond five years, and most current therapies have been unsuccessful in treating it.
The study, conducted in mice, opens a path for exploring treatments that combine epigenetic approaches with therapies that use the body’s natural immune response.
Research brief: Improving imaging processes will lead to more successful treatments and help reduce morbidity in men with the disease.
Research brief: The new finding highlights the need for alternative therapies for patients who are resistant to chemotherapy and radiation.
The new method should become the standard of care, say researchers from both universities who validated its effectiveness.
UCLA research paves the way for new diagnostic and therapeutic approaches.
In memoriam: Helene Brown, 91, ‘political oncologist’ who campaigned for cancer research, prevention
Brown, a UCLA alumna and member of UCLA’s Jonsson Comprehensive Cancer Center, died Oct. 4 at her home in Los Angeles.
Since first appearing in 2011, #BCSM has been used on the social media platform more than 830,000 times.
A pioneer in cancer immunology, Dr. Antoni Ribas has devoted his career to developing and refining new therapies for malignant melanoma.
The research opens up the possibility of using drugs that simulate viruses to overcome immunotherapy resistance in melanoma.
Spanning medicine, math and nanomaterials, support for campus scientific studies has grown almost 40% in five years.
The team will investigate the mechanisms of treatment resistance, laying the groundwork for new and improved combination therapies.
One of the most effective preventive measures is germline sequencing, which can detect gene mutations known to increase disease risk.
Research brief: UCLA researchers found that chemotherapy is often underutilized when treating adults with sarcoma, a rare type of cancer of the soft tissues or bone.
Research brief: A new combination treatment shows success in a mouse model of advanced head and neck carcinoma.