UCLA researchers were part of an international team to test gene therapy in people with X-linked chronic granulomatous disease.
Biomarker predicts which patients with heart failure have a higher risk of dying within 1 to 3 years
Scientists have been puzzled about why some people with heart failure live longer than others even after receiving the same treatment.
Scientists from 22 institutions, including UCLA, call for early diagnosis, prevention and treatment to reduce the risk of chronic diseases.
A Finnish study that included researchers from UCLA harnessed the DNA from nearly 20,000 people to identify genetic mutations that may increase the risk of diabetes, high cholesterol and other diseases and conditions.
A drug that suppresses the gene could lead to the first pill to treat stroke’s aftermath.
The findings could pave the way for new treatments for heart valve disorders, which can be caused by congenital defects, aging or disease.
High-density lipoprotein, or HDL, sometimes referred to as “good” cholesterol, is brought from the outer wall to the interior of the cell by a protein that helps create a “bridge” between the two areas.
Education and outpatient intervention programs are credited with improved patient outcomes.
The research, the first of its kind, also suggested that two new tests could help diagnose the condition, called autoimmune pulmonary alveolar proteinosis.
The research showed that a single session of hookah smoking increased heart rate and blood pressure; and significantly increased measures of arterial stiffness, a key risk factor in heart attack or stroke.
Research conducted between 2007 and 2009 showed that many patients were not receiving the recommended doses of three categories of medication.
Gil Solomon received a new aortic valve at UCLA that is more durable, reducing the need for an additional replacement when he is older.
The process analyzes several possible risk scenarios to help doctors more thoroughly assess people who could be candidates for heart transplants.
Women infected by the virus during pregnancy were 10 times more likely than the general population to give birth to babies with major cardiac problems, researchers found.
Study identifies receptor that may be targeted to repair the heart after heart attack, cardiac arrest
The discovery explains the mechanisms behind the protective effects of lipid emulsion therapy and could improve treatments for people with heart disease.
The UCLA-led research suggests that the ‘unexpected’ reason is a jump in heart disease risk for whites.
“Our ultimate goal is to be able to regenerate cardiomyocytes after an injury like a heart attack,” Dr. Reza Ardehali said. “But we’re first trying to learn from the embryonic heart.”
A UCLA-led study finds that the so-called “selfish” gene acts to remove cholesterol from blood vessels.
The analysis had a 93 percent accuracy rate for forecasting the chance of survival in people with advanced cardiac disease.
Under Affordable Care Act, Americans have had more preventive care for heart health, UCLA study finds
The results “provide people with more information to make a judgment about the value of the ACA,” said Dr. Joseph Ladapo, the study’s lead author.
The researchers believe this to be the first national study comparing statin use in patients with and without HIV and the first extensive analysis using U.S. data.
By having more accurate information, these adults and their physicians can make an informed decision on whether to undergo surgery, UCLA researchers concluded.
Researchers in the UCLA-led study concluded that better treatments for heart failure and new ways of predicting patient outcomes are needed.
UCLA researchers say the study challenges the concept that inhaled nicotine is benign, or safe.
The finding that heart failure is linked to how DNA is packaged within heart cells represents a new way to think about the development of heart disease and its treatment.