UCLA scientists were surprised to find that amyloid fibrils in brains with frontotemporal degeneration were composed of the little-known protein TMEM106B.
Dr. Ming Guo wants to help “create a higher quality of life over a healthy life span.”
The UCLA-led study, which used fruit flies, could also provide clues to a range of other diseases.
The findings could help scientists pinpoint targets for treating Parkinson’s and Huntington’s diseases.
The funds will support clinical and basic medical research under Dr. Rhonda Voskuhl, director of the UCLA Multiple Sclerosis Program.
The Ginsburg Center builds on teamwork among scientists and physicians to advance research, enhance patient care for genetic conditions.
A study in zebrafish identified how air pollutants contribute to the buildup of toxic proteins associated with the disease.
The contribution, from the Steven Gordon Family Foundation, will fund research, establish five faculty chairs and support a new lab where scientists can closely examine the mechanisms of the disease.
“This new tool makes possible experiments that we have been wanting to perform for many years,” said UCLA professor Baljit Khakh.
UCLA geneticist Dr. Wayne Grody UCLA geneticist says many people are ill-equipped to handle troubling medical information without the guidance of physicians.
Protein-imaging method developed by new UCLA researcher overcomes challenges of current techniques, offering untold potential in the exploration of disease and treatment.
The scientists believe the technique, which focuses on cells’ mitochondria, could eventually lead to a way to delay the onset of Parkinson’s disease, Alzheimer’s disease and cancer.
Researchers at UCLA have developed a molecular compound that improves balance and coordination in mice with the early stage of the disorder.
UCLA researchers note that the next decade shows great promise for things like improving food safety, fighting infections, storing energy and supplying clean energy.
Study finds that AT2101, a drug developed to treat Gaucher disease, helped halt the progression of Parkinson’s in mice.
The diverse group gathered at UCLA to learn about a bill authored by Assemblyman Ken Cooley that would require new football techniques and reduce high-impact contact during practice.
Led by Dr. Ming Guo, the team identified a new gene involved in the neurological disorder, a finding that could eventually lead to a new target for treatment.