Alzheimers

A molecule found in green tea helped UCLA biochemists discover several molecules that can destroy tau fibers.

UCLA scientists were surprised to find that amyloid fibrils in brains with frontotemporal degeneration were composed of the little-known protein TMEM106B.

Dr. Ming Guo wants to help “create a higher quality of life over a healthy life span.”

Research brief: Additional services to monitor the drug’s potential side effects account for nearly 20% of its total costs, a UCLA-led study shows.

The findings could help scientists pinpoint targets for treating Parkinson’s and Huntington’s diseases.

The funds will support clinical and basic medical research under Dr. Rhonda Voskuhl, director of the UCLA Multiple Sclerosis Program.

The Ginsburg Center builds on teamwork among scientists and physicians to advance research, enhance patient care for genetic conditions.

UCLA research suggests work can help preserve memory.

Proteins in the blood can be used to gauge a person’s risk for cerebral small vessel disease, which affects millions of older adults.

Identifying the characteristics of dementia that are caused by traumatic brain injury could prevent people from being misdiagnosed with Alzheimer’s disease.

A multi-disciplinary group of all-star researchers has been brought together thanks to a gift from philanthropists David and Diane Steffy.

Their findings could lead to new methods to get the body's repair enzyme to work better.

The research, conducted at the UCLA Alzheimer’s and Dementia Care Program, also shows that the program was cost-neutral after accounting for its costs.

The study is the most comprehensive published effort to date to identify the source of neurodegeneration across species.

The research by Dr. Lin Jiang and his team included findings from computer software that assisted them in the drug selection process.

The study not only revealed the promise of goal attainment in dementia care, but also the importance of goal setting for caregivers, who are affected both emotionally and physically by their loved one’s illness.

Neurophysicist Mayank Mehta’s work has implications for diagnosing and treating neurological diseases.

The research “may reassure some people that despite testing positive on screening tests, their chances of developing Alzheimer’s disease dementia is low,” said UCLA’s Ron Brookmeyer.

UCLA research provides critical knowledge for medicinal chemists to begin designing new drugs based on cambinol that are more potent than the molecule itself.

“This new tool makes possible experiments that we have been wanting to perform for many years,” said UCLA professor Baljit Khakh.

The scientists have shown in their research on mice that increasing levels of a protein could make immune cells more effective at fighting disease.

If replicated in larger studies, the findings could lead to new types of programs to improve mental agility in older adults by combining mental training with physical fitness.

UCLA geneticist Dr. Wayne Grody UCLA geneticist says many people are ill-equipped to handle troubling medical information without the guidance of physicians.

Protein-imaging method developed by new UCLA researcher overcomes challenges of current techniques, offering untold potential in the exploration of disease and treatment.

A UCLA study has found that moderate daily walks improve attention and mental skills for adults ages 60 and older.