UCLA scientists were surprised to find that amyloid fibrils in brains with frontotemporal degeneration were composed of the little-known protein TMEM106B.
Identifying the characteristics of dementia that are caused by traumatic brain injury could prevent people from being misdiagnosed with Alzheimer’s disease.
The research, conducted at the UCLA Alzheimer’s and Dementia Care Program, also shows that the program was cost-neutral after accounting for its costs.
The study not only revealed the promise of goal attainment in dementia care, but also the importance of goal setting for caregivers, who are affected both emotionally and physically by their loved one’s illness.
The research “may reassure some people that despite testing positive on screening tests, their chances of developing Alzheimer’s disease dementia is low,” said UCLA’s Ron Brookmeyer.
UCLA research provides critical knowledge for medicinal chemists to begin designing new drugs based on cambinol that are more potent than the molecule itself.