genetics

The continent’s diverse species all evolved very rapidly from a single ancestral population, a UCLA-led study shows.

Changes at the DNA level can accelerate aging by nearly five years, UCLA researchers and their colleagues report.

Understanding the adaptations that protect female animals from disorders may help humans too, UCLA research suggests.

The findings suggest that a drug used to treat HIV-related memory loss could combat cognitive decline in middle-aged people.

If they can escape death in poachers’ nets, the endangered marine mammal is well poised genetically to rebound despite inbreeding.

UCLA’s Dr. Manish Butte will head a group investigating immune responses to the disease, which is caused by fungal spores in soil.

Unless steps are taken to boost genetic diversity, local extinction remains a real threat, a UCLA-led study suggests.

Research brief: Adding a protein called viral polymerase to vaccines could potentially create a more robust, enduring immune response, scientists say.

UCLA researchers use super-resolution microscopy to reveal surprising new details about X inactivation in female mouse embryos.

Researchers report that all nine patients who were successfully treated for ADA-SCID in a UCLA clinical trial from 2009 to 2012 are still disease-free.

Too little sleep in the first six months after giving birth can add three to seven years to women’s “biological age,” UCLA scientists report.

A team led by UCLA scientists found that removing IGF2BP3 selectively targets cancer cells while leaving healthy cells alone.

Research brief: Scientists have identified hundreds of chemical modifications that can alter RNA’s protein-making instructions without affecting the core DNA.

By better understanding the dynamics of a key immune signaling molecule, scientists may be able to ‘hack’ the immune system to strengthen it.

The advance, researchers say, is like the cellular equivalent of discovering the Rosetta stone and may eventually lead to new treatments for diseases.

The treatment, developed by researchers from UCLA and the U.K., has restored immune function in more than 95% of patients in three clinical trials.

UCLA researchers and colleagues hope their first-of-its-kind catalog will reveal new targets for genetic and cell therapies for the disease.

The research, conducted on mice, targets a newly discovered molecular “checkpoint” that enables cancer stem cells to evade the immune system.

Research brief: A UCLA team has demonstrated that altering a key molecule used in the therapy yields superior and longer-lasting results in mouse models.

The project is the first to use the Nobel prize–winning technology to directly correct sickle mutation in blood stem cells.

Research brief: An approach pioneered at UCLA predicts which methicillin-resistant Staphylococcus aureus infections are likely to be cured with antibiotic therapy.

The Ginsburg Center builds on teamwork among scientists and physicians to advance research, enhance patient care for genetic conditions.

By identifying the underlying factors leading to bone loss and osteoporosis, UCLA dentist-scientists hope to pave the way to new treatments.

The first study to report genome-wide data on the prehistoric canid puts to bed a mystery biologists have pondered for more than 100 years.

UCLA astrophysicist Andrea Ghez and UC Berkeley biochemist Jennifer Doudna, both 2020 Nobel laureates, will be joined by climate change expert Emily A. Carter.