genetics

Research brief: UCLA scientists have discovered that histones act as an enzyme that converts copper into a usable form for cells.

Researchers will focus on an immunotherapy known as CAR T, which uses genetically modified stem cells to target and destroy the virus.

Research brief: Findings from a UCLA study indicate some men may not require the intensive treatment they have traditionally received.

The blood cells, part of the body's first line of defense against infection, have been notoriously difficult to genetically engineer.

The findings are critical for researchers aiming to develop muscle stem cells in the lab that can be used to combat disease.

“We hope our method could be used in the future to prepare treatments that can be performed at the patient’s bedside,” said UCLA’s Paul Weiss.

The interplay between estrogen and a key gene holds clues in the search for new therapies, biologists say.

Advanced statistical techniques enabled UCLA researchers to look backward in time hundreds of thousands of years without fossil DNA.

UCLA researchers were part of an international team to test gene therapy in people with X-linked chronic granulomatous disease.

The results should be useful to scientists studying genes involved in sleep, vision, memory and many other processes in humans.

UCLA researchers discovered differences in maternal and paternal X chromosomes that help explain sex differences in the immune system.

Degree program will help meet the rising demand for specialists trained to guide patients facing complex genetic disorders.

The study, conducted in mice, is the first to show that creatine uptake is critical to the anti-tumor activities of what is known as killer T cells, the foot soldiers of the immune system.

Arginase deficiency, which is caused by a missing or mutated version of the arginase gene, ARG1, affects about one of every 1 million babies in the U.S.

Research brief: A gene on the X-chromosome may help explain why more women than men develop autoimmune diseases, including multiple sclerosis.

A Finnish study that included researchers from UCLA harnessed the DNA from nearly 20,000 people to identify genetic mutations that may increase the risk of diabetes, high cholesterol and other diseases and conditions.

The discoveries by an interdisciplinary team of UCLA scientists could improve the diagnoses of these aggressive cancers.

The findings have implications for the conservation of rare and endangered species, in which low genetic diversity could increase the odds of extinction.

UCLA researchers launch open-source software that can identify a broad range of species from samples.

The findings will both help identify women who are at highest risk of developing ovarian cancer and pave the way for identifying new therapies that can target these specific genes.

The UCLA-led group has created an online resource guide to help scientists in lower-income countries jumpstart research programs.

“This is a pervasive, global problem.... It’s in all types of landscapes — urban, rural and even untouched environments,” says Seth Riley, a co-author of the research.

The study suggests that silencing, or blocking the expression of a particular protein by using a patented technology may offer a new treatment.

Changes in RNA editing play an important role in the disorder, scientists find.

UCLA’s Dr. Michael Gandal said that beyond the important new findings, he is even more optimistic about what the data will help researchers learn in the future.